He joined Watford straight from school in July 1975. Making his debut in the 1975-76 season, he gained a regular place in the side in 1977-78 season as Watford gained promotion to Division Three. His powerful running and superb aerial ability, in addition to a noteworthy contribution of 21 League goals, helped propel Watford to Division Two the following season.
Winning the first of his four England under-21 caps in 1979, Luther Blissett went on to represent England at full international level, winning 14 caps. He became England's first black goalscorer with a hat-trick in his first start, a 9-0 win over Luxembourg in 1982.
After assisting Watford to Division One and finishing as top scorer in three of his last four seasons, Blissett joined AC Milan for £980,000 in June 1983. Rejoining Watford in August 1984 after 30 appearances in Serie A, he remained at Vicarage Road until November 1987. Making his second return in 1991, Blissett holds records at Watford for 415 league appearances and 158 league goals scored.
He went on to become a member of the coaching staff at Watford with responsibility for coaching the reserve team before becoming manager of Chesham United in the Southern League, Division 1 (South and West) in 2006. He has gone on to manage or coach a number of lower league and non-league clubs.